Each will receive $500,000 over the next five years:
Marin Alsop, 48, principal conductor, England's Bournemouth Symphony Orchestra; music director, Baltimore Symphony Orchestra.
Terry Belanger, 64, professor, University of Virginia; founded the Rare Book School, a nonprofit institute devoted to the histories of manuscripts, print, and electronic text.
Edet Belzberg, 35, documentary filmmaker, New York; best known for ''Children Underground," about a group of homeless children living in a Romanian train station.
Majora Carter, 38, urban strategist, New York; founder, executive director of Sustainable South Bronx, which seeks to create new opportunities for recreation, nutrition, transit, and development.
Lu Chen, 33, assistant professor of neurobiology at the University of California, Berkeley; her work with the synapse sheds light on the biology of learning and memory.
Michael Cohen, 61, president, Institute for Safe Medication Practices in Huntingdon Valley, Pa.; a pharmacist who has worked to reduce preventable drug and drug delivery mistakes.
Joseph Curtin, 52, principal, Joseph Curtin Studios, Ann
Aaron Dworkin, 35, founder, president of the Detroit-based Sphinx Organization; he seeks to increase the numbers of minorities in classical music careers.
Teresita Fernandez, 37, sculptor, New York; integrates architecture and common building materials into her work.
Claire Gmachl, 38, associate professor of electrical engineering, Princeton University; works in the fields of optics and semiconductor laser technology.
Steven Goodman, 48, field biologist, The Field Museum, Chicago; he lives in Madagascar, where he works to document and protect endangered plants and animals.
Pehr Harbury, 40, associate professor of biochemistry, Stanford University; a biochemist whose work focuses on the structure and activity of proteins.
Nicole King, 35, assistant professor of molecular and cell biology, University of California, Berkeley; her work seeks to reconstruct the emergence of multicellular organisms that form the base of the animal kingdom.
Jon Kleinberg, 33, professor of computer science, Cornell University; a computer scientist whose research topics have tackled a wide variety of practical problems.
Jonathan Lethem, 41, novelist, Brooklyn, N.Y.; the author of six novels, including ''Motherless Brooklyn" and ''The Fortress of Solitude," which won the National Book Critics Circle award.
Michael Manga, 37, associate professor of earth and planetary science, University of California, Berkeley; a geophysicist who has explored phenomena ranging in scale from microscopic to planetary.
Todd Martinez, 37, professor of chemistry, University of Illinois, Urbana-Champaign; a theoretical chemist who has developed new strategies that provide insight into the physical basis for chemical reactions.
Julie Mehretu, 34, painter, New York; her work evokes multiple time periods and locales.
Kevin M. Murphy, 47, professor, University of Chicago Graduate School of Business; an economist whose work has examined how economic forces influence social phenomena, including unemployment.
Olufunmilayo Olopade, 48, professor of medicine and human genetics, University of Chicago Hospitals; a physician and researcher who has focused on breast cancer in women of African descent.
Fazal Sheikh, 40, documentary photographer, Zurich; he uses portraiture to depict the faces of the world's displaced people, such as survivors of the Soviet occupation of Afghanistan.
Emily Thompson, 43, associate professor of history, University of California, San Diego; an aural historian whose work has touched on everything from urban design to cinema studies.
Michael Walsh, 62, technical consultant, Arlington, Va.; a vehicle emissions specialist who is working to improve the environment by reducing the effect of internal combustion engines.