After his playing days, Tatupu turned to coaching. He coached the football team at King Philip Regional High School (pictured) in Wrentham in 1995 and he was later a running backs coach at Curry College in Milton.
In 1992, The Simpsons television program referenced Tatupu, who is Samoan. "Mosi Tatupu, Mosi Tatupu," a tribal chief said in one episode. This translated to "The blue-haired women will make a good sacrifice."