Brady playing at Harvard on Friday as kick off to Best Buddies weekend

The Patriots wrap up a second week of organized team activities in Foxborough on Thursday -- but Tom Brady plans on throwing the football around on Friday, too. Joined by teammates, celebrities, other athletes, and more, the quarterback will be at Harvard Stadium for the annual Tom Brady Football Challenge.

Kickoff is at 6 p.m., with the program starting 15 minutes earlier, and tickets are free (though they must be reserved here beforehand). The flag football game is held in conjunction with the Best Buddies Challenge, which will follow a day later, but Brady announced last month that money raised Friday night will be donated to the One Fund Boston and victims of April's marathon bombing.

As for Saturday's Best Buddies Challenge, it benefits an organization Brady has been involved with for 12 years, and is the first of four 2013 events nationally. It features a 100-mile bike ride winding from the JFK Presidential Library to Hyannis Port, though riders can join in Carver for the final 50 miles, or in Sandwich for the final 20 miles. The bikers will be joined along the way by cycling legend George Hincapie, while there's also a 5k run/walk that takes place in Hyannis Port, and that will be led by Olympic icon Carl Lewis.

Brady, who is the event chair, will be among those waiting for everybody at the finish line -- where all participants will celebrate at a private beach-side party with gourmet food, an open bar, celebrity guests, and concert by Dennis DeYoung (of Styx).

More than 1,500 people are expected to participate -- registration is still open -- including some of those who will benefit from the money raised in support of Best Buddies International, a non-profit dedicated to enhancing the lives of people with intellectual disabilities. Last year's Hyannis Port event raised $3 million-$4 million, according to Brady, who would like to see that number climb this time around.

"Hopefully we can do more this year," he said in a recent appearance on WEEI. "Come on out, it's a great event, a lot of my teammates will be there and it's really the highlight of my offseason."