Oakland won the season series against Seattle for the first time since 2000.
Angels' Vladimir Guerrero matched a career high for hits with his fifth four-hit game this season and 15th in his career. It was the second two-homer game this week for Guerrero, who has 38 this year and is hitting .338 with a team-record 123 runs and 124 RBIs in his first Anaheim season. He was 12 for 17 with five homers and nine RBIs in the four-game series against Texas.
Seattle's Edgar Martinez, who will retire at the end of the season, was honored before the game at Networks Associates Coliseum.