
It was the
biggest new VC fund to raise money in the first quarter of 2010 — a shade over $50 million — but no one is yet saying much about it. There's no Web site yet, and no timeframe for divulging much more, I'm told.
It's the Longwood Founders Fund, and the three partners are local biotech biggies Christoph Westphal, Michelle Dipp, and Rich Aldrich. Westphal and Dipp are Cambridge-based executives at GlaxoSmithKline, which
acquired their company Sirtris in 2008 for $720 million; Aldrich runs
RA Capital Management, the Back Bay investment firm.
But the new firm is a sponsor of today's
Boston Biotech Business Development Conference in Cambridge, a long-running event that Westphal, Dipp, and Aldrich are involved in organizing, along with a handful of other local life sciences notables.
Several local venture capitalists tell me that Glaxo is a major investor in the new Longwood fund, but Westphal wouldn't confirm that today. The big question is that if Westphal is spending time scouting life sciences investments for the new fund, will he dial down (or suspend) his current activities within Glaxo, where he is both chief executive of Sirtris and a senior vice president of Glaxo's Centre for Excellence in External Drug Discovery? Before starting Sirtris in 2004, Westphal was an investor a Polaris Venture Partners in Waltham, and was also briefly chairman of the life sciences advisory board at Boston-based IDG Ventures (now Flybridge Capital Partners.) As an investor, interim CEO, and board member, Westphal also helped launch local biotech companies like Alnylam, Momenta, and Concert Pharmaceuticals.
Ansbert Gadicke, managing partner at MPM Capital in Boston, says he expects the Longwood Founders Fund to invest in one or two early-stage life sciences start-ups a year. "I could imagine that we'll probably wind up co-investing with them," says Gadicke.
My expectation is that Glaxo may bring in a new CEO to run Sirtris at some point, freeing up more of Westphal's time to source new investments, assemble teams, and help companies begin the process of turning science into product. (Sirtris is still traveling that road, with several
new drug candidates still in FDA Phase IIa clinical trials, despite a
glowing feature on "60 Minutes" last year.) Gadicke says that giving Westphal a new set of responsibilities involving making investments — a demonstrated strength of his — "is a perfect way for him to stick around in a big company."
Glaxo spokesperson Mary Anne Rhyne told me yesterday that Westphal and Dipp remain employees of the company, but that she wouldn't comment as to whether Glaxo is an investor in the Longwood Founders Fund. Glaxo already operates a corporate venture capital fund of its own, Pennsylvania-based
SR One, which got started back in 1985.
Aldrich at RA Capital didn't respond to a phone call and e-mail yesterday.