BUDDY-BUDDY7. E and Vince, "Entourage"
There are four guys on this show, but Turtle and Drama are mostly comic relief. The bond between E (left) and Vince (right) is what truly keeps the storyline afloat, as they make — and unmake, and remake — Vince's career together.
Pictured: Kevin Connolly as "E" (left) and Adrian Grenier as Vince.